Boaz Avitall

Boaz Avitall

USA

 

 

 

 

Professor of Medicine
Director of Cardiac Electrophysiology
Electrophysiologist
Research and Academic Interests
• Catheter ablation of atrial fibrillation
• Basic cardiac electrophysiology, cardiac arrhythmia, pacing, defibrillation, drug transport, radiofrequency tissue ablation, CRYO and chemical ablation
• Computerized system, biomedical systems and instrumentation design
• Cardiovascular experimental surgery (acute and chronic), isolated perfused cardiac muscle, and isolated perfused heart
• Cardiac electrophysiology instrumentation and catheter design Clinical Interests
• Cardiology
• Heart Rhythm Management
• Ablation of Cardiac Arrhythmia
• Pacemakers and Defibrillators
• Cardiac Rhythm Monitoring
28 patents including the original CRYO balloon for PVI isolation.
Selected Publications :
1. Mohammad JR, Hempe SL, Sra S, Dhala A, Blanck Z, Deshpande SS, Avitall B, Krum DP, Gilbert CJ, Akhtar M: Selective transcatheter ablation of the fast and slow pathways using radiofrequency energy in patients with atrioventricular nodal reentrant tachycardia. Circ 85:1318-1328,1992.
2. Akhtar M, Avitall B, Mohammad JR, Tchou P, Troup PJ: Role of implantable cardioverter defibrillator therapy in the management of high-risk patients. Circ 85(suppl I):131-139,1992.32.
3. Khan M, Dhala A, Hare J, Avitall B: Percutaneous transcatheter ablation for cardiac arrhythmias.
Cardio July 1992, p47-p54.
4. Avitall B, Khan M, Krum D, Hare J, Lessila C, Dhala A, Deshpande S, Jazayeri M, Sra J, Akhtar M: The physics and engineering of transcatheter cardiac tissue ablation. JACC 22:921-932, 1993.
5. Avitall B, Hare J, Khan M, Zander G, Lessila C, Dhala A, Deshpande S, Jazayeri M, Sra J, Akhtar M: Cardioversion, defibrillation and overdrive pacing of ventricular arrhythmias: The effect of moricizine in dogs with sustained monomorphic ventricular tachycardia. Pace and Clinical Electrophysiology 16:2092-2097;1993.
6. Sra JS, Jazayeri MR, Avitall B, Dhala A, Deshpande S, Balnck Z, Akhtar M: Comparison of cardiac pacing with drug therapy in the treatment of neurocardiogenic (vasovagal) syncope with bradycardia or asystole. N Engl J Med. 328:1085-1090;1993.
7. Avitall B, Mughal K, Krum D, Jazayeri M, Hare J: The repeated use of ablation catheters: a prospective study. JACC 22:1367-1372;1993.
8. Jazayeri M, Sra J, Deshpande S, Blanck Z, Dhala A, Krum D, Avitall B, Akhtar M: Electrophysiologic Spectrum of Atrioventricular Nodal Reentrant Tachycardia Undergoing Selective Fast or Slow Pathway Ablation. J Cardiovasc. Electrophysiol 4:99-111;1993.
9. Avitall B, Hare J, Krum D, Dhala A, Sheth M, Deshpande S, Jazayeri M, Sra J, Akhtar M: The Anatomical Determinants for the Design of Intracardiac Mapping and Ablation Catheters. Pace and Clinical Electrophysiology. 17(5 Pt. 1):908-918,1994.
10. Avitall B. Stormo A, Barragry T, Axtel K, Hare J: Sudden Cardiac Death: Twiddler’s Syndrome with an Implantable Cardioverter Defibrillator. Am Heart J. 128:833-6, 1994
11. Avitall B. Catheter Ablation of Cardiac Arrhythmias: Future Technologies. CARDIO:S32-6; November, 1994.
12. O’Hara M, Yu X, Mehdi N, Schwartz C, Wu D, Avitall B, He B. Body Surface Laplacian Mapping of Ventricular Depolarization from Potential Recordings in Humans. Proceedings of the Annual International Conference of IEEE Engineering in Medicine and Biology Society. 1995.
13. Avitall B, Mughal K, Hare J, Silverstien E, Krum D, Helms R. The Effects of Electrode-tissue Contact on Radiofrequency Lesion Generation. Pace and Clinical Electrophysiology, 20:12 Pt 1:2899-2910,1997.
14. Avitall B, Helms R, Koblish J, Sieban W, Kotov A, Gupta G. The Creation of Linear Contiguous Lesions in the Atria with an Expandable Loop Catheter. J Am Coll Cardiol. 1999 Mar 15;33(4):972-84.
15. Avitall B, Urbonas A, Urboniene D, Millard S, Helms R. The time course of left atrial mechanical recovery after linear lesions: normal sinus rhythm versus a chronic atrial fibrillation dog model. J Cardiovasc Electrophysiol 2000; 11:1397-1406.
16. Avitall B, Urbonas A, Millard S, Urboniene D, Helms R. Ablation of atrial fibrillation in the rapid pacing canine model using a multi-electrode loop catheter. J Am Coll Cardiol 2001; 37(6):1733-1740.
17. Avitall B, Urbonas A, Urboniene D, Malhotra V, Millard S. The ablation of atrial fibrillation with the loop catheter design: what we have learned from the animal model. Journal of Pacing and Clinical Electrophysiology, Vol.24, No.7, July 2001.
18. TsaiH, Ceccoli H, Avitall B, He B. Body Surface Laplacian Mapping of Anterior Myocardial Infarction in Man. Electromagnetics, 21:607-619, 2001.
19. Li G, Lian J, Salla P, Cheng J, Shah P, Ramachandra I,Avitall B, He B. Body Surface Laplacian ECG Mapping of Ventricular Depolarization in Normal Subjects. Journal of Cardiovascular Electrophysiology, 2003,Jan;14(1):16-
20. Lian J, Li G, Cheng J, Avitall B, He B. Body Surface Laplacian ECG Mapping of Atrial Activation in Normal Subjects. Medical & Biological Engineering & Computing, 40(6): 650-659, 2002.
21. Lian J, Srinivasan S, Tsai HC, Wu D, Avitall B, and He B. Estimation of Noise Level and Signal to Noise Ratio of Laplacian ECG During Ventricular Depolarization and Repolarization. Pacing and Clinical Electrophysiology, 25(10): 1474-1487, 2002.
22. Avitall B, Urbonas A, Urboniene D, Rozmus G, Helms R. Linear Lesions Provide Protection from Atrial Fibrillation Induction with Rapid Atrial Pacing. J Cardiovasc Electrophysiol 2002; 13:455-462.
23. Benatar D, Bondmass M, Ghitelman J, Avitall B. Outcomes of chronic heart failure. Arch Intern Med 2003 Feb 10;163(3):347-52.
24. Avitall B, Urboniene D, Rozmus G, Lafontaine D, Helms R, Urbonas A. New Cryo Technology for Electrical Isolation of the Pulmonary Veins. J Cardiovascular Electrophysiol 14(3):281-286,2003.
25. Avitall B, Urbonas Arvydas, Lafontaine D, Rozmus G, Adoni N. Ablation of Atrial Ventricular Junction Tissues via the Coronary Sinus Using Cryo Balloon Technology. JICE 12(3): 203-211, 2005.
26. Avitall B, Urbonas Arvydas, Lafontaine D, Rozmus G, Adoni N. The Safety and Efficacy of Multiple Consecutive Cryo Lesions in Canine Pulmonary Veins Left Atrial Junction. Heart Rhythm 1:204-209,2004.
27. Avitall B, Bi J, Mykytsey A, Chicos A. Atrial and ventricular fibrosis induced by atrial fibrillation: Evidence to support early rhythm control. Heart Rhythm 2008 Jun 5(6):839-45
28. Lavi N, Sogaard P, Mykytsey A, Willard M, Hastings H, Latchamsetty R,Avitall B. Bi-Ventricular Endocardial pacing is Superior to Traditional Epicardial Pacing Via the Coronary Sinus for Left Ventricular Synchronization in a Tachycardia Induced Heart Failure Model. In review Circulation
29. Pawan K. Arora, James C. Hansen, Adam D. Price, Josef Koblish, Boaz Avitall. An Update on the Energy Sources and Catheter Technology for the Ablation of Atrial Fibrillation. JAFIB.2010 March Arora PK., Hansen J, Latchamsetty Rh, Avitall B. Is Cryo A Better Energy Source Than Radiofrequency For AF Ablation In Preventing Esophageal Injury? .JAFIB.2009 April;Volume 1 Issue(6): 321-327.
30. Arora PK., Hansen J, Latchamsetty Rh, Avitall B. Is Cryo A Better Energy Source Than Radiofrequency For AF Ablation In Preventing Esophageal Injury? .JAFIB.2009 April;Volume 1 Issue(6): 321-327.
31. Hansen JC., Latchamsetty R, Lavi N, Uppuluri S, Lafontaine D, Hastings R and Avitall B. High-density biatrial pacing protects against atrial fibrillation by synchronizing left atrial tissue. Journal of Interventional Cardiac Electrophysiology Volume 27, Number 2, 81-87,2010.
32. Price, Adam, Z. Leshen, J. Hansen, I. Singh, P. Arora, J. Koblish, and B. Avitall. “Novel ablation catheter technology that improves mapping resolution and monitoring of lesion maturation.”Innov Cardiac Rhythm Management3 (2012): 599-609.
33. Singh, Inderpal, Adam Price, Boaz Avitall, and Zachary Leshen.Past, Present and Future Catheter Technologies and Energy Sources for Atrial Fibrillation Ablation. INTECH Open Access Publisher, 2012.
34. Avitall, Boaz, Piotr Horbal, David Vance, and Josef Koblish. “Determinants of atrial lesion maturation during radio frequency ablation using localized tissue electrograms.”J Innov Cardiac Rhythm Management 5 (2014): 1574-1585.
35. Avitall, Boaz, Piotr Horbal, David Vance, Josef Koblish, and Arthur Kalinski. Maximal Electrogram Attenuation Recorded from Mini Electrodes Embedded on 4.5‐mm Irrigated and 8‐mm Non-irrigated Catheters Signifies Lesion Maturation.Journal of cardiovascular electrophysiology26, no. 2 (2015): 192-202.
36. Avitall, Boaz, and Arthur Kalinski. “Cryotherapy of Cardiac Arrhythmia: From Basic Science to the Bedside.” Heart Rhythm (May 2015).